Reza Mahdavi; Fatemeh Ghannadiasl; Mohammad Asghari Jafarabadi
Volume 20, s1 , December 2018, , Pages 1-8
Abstract
Background: The use of weight-loss dieting has always been overemphasized as the first modality to treat obesity. Success in weight loss is considered a major problem in obese individuals. The processes of behavior change have been used to facilitate intervention promoting change. Only a minority of ...
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Background: The use of weight-loss dieting has always been overemphasized as the first modality to treat obesity. Success in weight loss is considered a major problem in obese individuals. The processes of behavior change have been used to facilitate intervention promoting change. Only a minority of studies have employed this construct for weight loss.Objectives: The purpose of this study was to assess the effect of a balanced low-calorie diet with or without nutrition education on the weight loss and processes of change among obese women. Methods: In a randomized clinical trial, 90 apparently healthy obese women age 18 - 50 with body mass index (BMI) of 30 - 40 kg/m2 were recruited from the nutrition clinic in Ardabil, located in the northwest of Iran. Participants were assigned randomly to receivea balanced low-calorie diet with or without nutrition education. Participants completed a processes of change questionnaire at baseline and at three and six months after intervention. A generalized linear model repeated measures analysis of variances was used to assess the time effect as well as the interaction between the time and the group effect.Results: Significant differences were found in the time effect for weight (F = 12.64, df = 2, P < 0.001), BMI (F = 10.90, df = 2, P = 0.001), andcounterconditioning (F = 22.82, df = 2, P < 0.001), and helping relationships (F = 5.47, df = 2, P = 0.006), reinforcement management (F = 3.65, df = 2, P = 0.03), self-liberation (F = 5.05, df = 2, P = 0.008), stimulus control (F = 12.12, df = 2, P < 0.001), and substance abuse subscales (F = 6.72, df = 2, P = 0.002). Significant differences were shown in interaction time and group effect for weight (F = 5.69, df = 2, P = 0.011), BMI (F = 4.91, df = 2, P = 0.018) and counterconditioning (F = 5.11, df = 2, P = 0.008) and stimulus control (F = 5.50, df = 2, P = 0.006) subscales. Conclusions: The findings support the use of nutrition education for more weight loss and improvement in the counter condition- ing and stimulus control subscales among obese women attending the nutrition clinic. It seems that nutrition education should be considered important in effective weight-loss interventions.
Nasim Abedimanesh; Alireza Ostadrahimi; S Zahra Bathaie; Saeed Abedimanesh; Behrooz Motlagh; Mohammad Asghari Jafarabadi
Volume 19, Issue 9 , September 2017, , Pages 1-8
Abstract
Background: Depression and sexual problems are common in patients with coronary artery disease (CAD) and can influence their quality of life.Objectives: The aim of this study was to compare the efficacy of saffron and its main constituent, crocin, in improving mental and sexual health and ultimately ...
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Background: Depression and sexual problems are common in patients with coronary artery disease (CAD) and can influence their quality of life.Objectives: The aim of this study was to compare the efficacy of saffron and its main constituent, crocin, in improving mental and sexual health and ultimately quality of life in CAD patients.Methods: This double-blind, placebo-controlled, randomized clinical trial was carried out during 8 weeks in 3 groups, including 1 placebo and 2 intervention groups. The study sample included 58 CAD patients within the age range of 40 - 65 years, referred to Shahid Madani cardiovascular hospital, Tabriz, Iran, from April 2015 to November 2016. The intervention groups received saffron aqueous extract (SAE; 30 mg; n, 20) or crocin (30 mg; n, 19). All the groups completed the demographic questionnaire, Beck depression inventory-II (BDI-II), Hulbert index of sexual desire (HISD), and MacNew health-related quality of life questionnaire.Results: The BDI-II score significantly decreased in the SAE (pre- and post test scores, 26.10 ± 11.98 and 21.05 ± 9.93, respectively) and crocin (pre- and post test scores, 27.89 ± 8.46 and 22.68 ± 8.01, respectively) groups (P < 0.001). After adjustments for age, sex, and diagnosis time, similar results were obtained. There was no significant difference between the crocin and SAE groups in terms of total BDI-II score at the end of the study (P = 0.999). SAE and crocin had no significant effects on HISD scores (P = 0.148 and 0.317, respectively). However, they could significantly improve the total quality of life and its subscales (P < 0.001).Conclusions: SAE and crocin could improve depression and health-related quality of life in patients with CAD, whereas they had no significant effects on sexual desire.
Mojgan Mirghafourvand; Sakineh Mohammad -Alizadeh-Charandabi; Mohammad Asghari Jafarabadi; Azam Mohammadi; Sedigheh Soltanpour
Volume 19, Issue 5 , May 2017, , Pages 1-9
Abstract
Background: The functional status questionnaire is aimed as a self-administered functional assessment of the mothers’ performance in the postpartum period based on five different areas, including baby care, personal care, household, social and community, and occupational activities.Objectives: ...
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Background: The functional status questionnaire is aimed as a self-administered functional assessment of the mothers’ performance in the postpartum period based on five different areas, including baby care, personal care, household, social and community, and occupational activities.Objectives: The aim of this study was to evaluate the psychometric properties of the functional status questionnaire for assessing Iranian women in the postpartum period.Methods: In this cross-sectional, methodological study, 200 Iranian women were selected randomly via a two-stage cluster sampling method at the end of the postpartum 6th week from healthcare centers in six areas of Tehran (the capital of Iran). The translation validity of the questionnaire was confirmed by forward and backward translation. Content-related validity was determined in two qualitative and quantitative sections, respectively, by evaluating the experts’ opinions and calculating of content validity ratio (CVR) and content validity index (CVI), while the face validity was evaluated by a sample of 30 mothers in the postpartum period. To determine the construct validity, exploratory factor analysis was used. The reliability was determined in terms of reproducibility via the intra-class correlation coefficient (ICC) by test-retest and internal consistency (Cronbach’s alpha).Results: The CVI and CVR as the indices for content validity were 0.88 and 0.82, respectively. Further, the reliability was good, both in terms of reproducibility (ICC = 0.96) and internal consistency (α= 0.73). The construct validity was also supported by the exploratory factor analysis for all four areas of functional status. The Kaiser-Meyer-Olkin (KMO) index of household, social and community, baby care, and personal care activities subscales was calculated as 0.85, 0.85, 0.56, and 0.50, respectively. The total variance (%) for household activities, social and community, baby care, and personal care was 56.86, 53.94, 38.07, and 43.39. All items with a minimum and maximum factor loading of 0.2 and 0.96 are placed at the right factor.Conclusions: The findings support the instrument’s validity and reliability. Therefore, it is recommended to be used for both clinical and research purposes.
Leila Valizadeh; Mahasti Alizadeh; Mohammad Asghari Jafarabadi; Parvaneh Aghajari; Zeynab Mousarrezaei
Volume 19, Issue 3 , March 2017, , Pages 1-8
Abstract
Background: Sleep-deprivation in children decreases the quality of life and endangers health. Increasing mother’s level of awareness can help improve the children’s sleep schedule and avoid many associated problems.Objectives: This study aimed to investigate the effect of SMS-based education ...
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Background: Sleep-deprivation in children decreases the quality of life and endangers health. Increasing mother’s level of awareness can help improve the children’s sleep schedule and avoid many associated problems.Objectives: This study aimed to investigate the effect of SMS-based education on the level of sleep knowledge in mothers with 7 - 12 years old children.Methods: In this single-blind randomized controlled trial, 13 governmental primary schools in Tabriz (Iran) in 2016 (7 girls’ schools and 6 boys’ schools) were randomly selected among the primary schools, using cluster sampling approach. Then, the mothers of sleep-deprived students were randomly divided into intervention and control groups by using RAS. Both of the groups took a pretest on sleep knowledge by PSKI and then, mothers in the intervention group received education through sending SMS. Finally, all of the participants took again the posttest in two time intervals including a week and three months after the intervention. A number of 92 mothers (experiment = 47, control = 45) completed all of the three phases of the research and the data were analyzed using SPSS ver13.Results: The results showed that the difference between the scores obtained in the first and the second measurements of sleep knowledge in the experimental group was significantly different from that of the control group [mean between-group difference of 5.98 within 95% CI of 3.56 to 8.41 (P < 0.001)]. The difference of sleep knowledge scores between the third and first measurements in the experimental group was also significantly different from that of the control group [mean between-group difference of 4.09 within 95% CI of 1.44 to 6.74 (P < 0.003)].Conclusions: The use of SMS-based education is a constant and efficient educational approach for increasing mothers’ level of knowledge about children’s sleep health.
Neda Gilani; Anoshirvan Kazemnejad; Farid Zayeri; Mohammad Asghari Jafarabadi; Fatemeh Sadat Izadi Avanji
Volume 19, Issue 2 , February 2017, , Pages 1-7
Abstract
Background: Traumatic brain injury (TBI) is an important public health problem throughout the world.Objectives: The aim of this study was to assess repeated glasgow coma scale (GCS) scores in predicting the severity of TBI and patients’ survival.Patients and Methods: In this longitudinal study ...
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Background: Traumatic brain injury (TBI) is an important public health problem throughout the world.Objectives: The aim of this study was to assess repeated glasgow coma scale (GCS) scores in predicting the severity of TBI and patients’ survival.Patients and Methods: In this longitudinal study used a total sample of 239 patients, all of whom were hospitalized with traumatic brain injuries. Subjects were selected by simple random sampling in intensive care unit (ICU) wards of the Shahid Beheshti hospital in Kashan, Iran between September 2008 and September 2010. The patients’ level of consciousness was evaluated using GCS at admission, six hours after admission to the ICU, and at the time of discharge from the hospital. A Glasgow outcome score (GOS) is used to classify the global outcomes in TBI survivors. A joint modeling approach was utilized for data analysis using R software.Results: The results showed that female patients had the risk of occurrence, slightly more than men, but this was not significant(HR =1.095 P = 0.757). The mortality risk was significantly higher in older patients (HR = 1.010, P = 0.010). In addition, the resultsindicated a significant increasing linear trend in GCS values over time (HR=1.78, P=0.003). Higher age was also associated with lowerGCS values over time (P < 0.001). The severity of TBI decreases with increasing GCS values (P < 0.001).Conclusions: By jointly modeling longitudinal data with time-to-event outcomes, our findings supported the use of the GCS scoresin predicting the severity of TBI.
Somayeh Mohammadi; Seyed Rafie Arefhosseini; Mohammad Asghari Jafarabadi; Zarin Sharifnia; Mehrangiz Ebrahimi-Mameghani
Volume 19, Issue 1 , January 2017, , Pages 1-8
Abstract
Background: Obesity is the main cause of insulin resistance and type 2 diabetes mellitus (T2DM). Diet therapy is the cornerstone in the management of obesity and T2DM.Objectives: We evaluated the effects of calorie-restricted diet therapy on the circulating level of the serum lipid profile, glucose, ...
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Background: Obesity is the main cause of insulin resistance and type 2 diabetes mellitus (T2DM). Diet therapy is the cornerstone in the management of obesity and T2DM.Objectives: We evaluated the effects of calorie-restricted diet therapy on the circulating level of the serum lipid profile, glucose, insulin, and adiponectin in obese women with T2DM.Materials and Methods: This randomized clinical controlled trial was performed for 10 weeks on 30 eligible obese T2DM women distributed to control (n = 15) and diet therapy (n = 15) groups. Demographic, nutritional, anthropometric, and laboratory data were obtained before and after the study. Data were analyzed by SPSS vs.15 and Nutritionist IV.Results: In addition to anthropometric measurements, diet therapy independently improved fasting blood sugar (P = 0.024, -69.37 to -5.57 mg/dL), 2-h postprandial blood sugar (P = 0.007, -123.34 to -22.3 mg/dL), serum total cholesterol (P = 0.005, -46.48 to -9.72 mg/dL), serum alanine transaminase (P = 0.001, -8.91 to -3.18 U/L), and increased circulating adiponectin (P = 0.038, 0.01 to 0.47 µg/mL).Conclusions: Improvement of biomarkers of insulin sensitivity, including adiponectin and lipid metabolism, is an important therapeutic effect of medical nutrition therapy in obese patients with T2DM.
Maryam Rafraf; Salar Hemmati; Mohammad Asghari Jafarabadi; Abdolvahab Moghaddam; Mahdiyeh Khadem Haghighian
Volume 19, Issue 1 , January 2017, , Pages 1-8
Abstract
Background: Osteoarthritis (OA) is a degenerative joint disease with several pathological mechanisms. The intervention that provides for reduced pain and disability with fewer side effects may help improve OA. Pomegranate peel is known to have powerful antioxidant and anti-inflammatory properties due ...
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Background: Osteoarthritis (OA) is a degenerative joint disease with several pathological mechanisms. The intervention that provides for reduced pain and disability with fewer side effects may help improve OA. Pomegranate peel is known to have powerful antioxidant and anti-inflammatory properties due to its great amount of polyphenols.Objectives: The objective of this study was to evaluate the effects of the pomegranate peel extract on clinical signs and symptoms of knee OA.Methods: This randomized, doubleblind placebo-controlled clinical trial was conducted amongst 60 women in the age range of 38 - 60 years who were referred to the physical medicine and rehabilitation department of the Tabriz University of Medical Sciences in Tabriz, Iran (Sep 2014 - Feb 2015). The participants were allocated using the block randomization method in one of two study arms. The intervention and control groups received 500 mg of pomegranate peel, hydro alcoholic extract (n = 30) and placebo (n = 30), twice daily for 8 weeks, along with standard drug therapy. The primary outcome measure was the change in mean, Knee injury and osteoarthritis outcome score (KOOS) and the secondary outcome measure was the visual analog scale score.Results: There were no significant differences between the two groups in the mean of age, body mass index (BMI), disease duration and parity before intervention (P > 0.05). The mean of KOOS increased from 46.15 ± 16.82 to 57.57 ± 15.61 after 12 weeks (P < 0.001) as compared to the placebo group 50.83 ± 18.83 declining to 56.10 ± 18.07 (P < 0.001). The VAS score declined significantly in both treatment and control groups compared with baselines (P < 0.005). These changes in the intervention group were significantly greater than those in the control group after adjusting for baseline values, weight changes, energy intake, physical activity, disease duration and parity (P < 0.05).Conclusions:This study presented some effects of the pomegranate peel extract in reducing pain and improving clinical signs and symptoms in women with knee OA and might be considered as a complementary medicine in treating OA.
Somayeh Mohammadi; Mehrangiz Ebrahimi-Mameghani; Seyed Rafie Arefhosseini; Parviz Fallah; Mohammad Asghari Jafarabadi; Sepideh Zununi; Masoud Soleimani; Mehdi Banitalebi Dehkordi; Hossein Ghanbarian
Volume 19, Issue 1 , January 2017, , Pages 1-10
Abstract
Background: MicroRNAs have recently been introduced as epigenetic regulators of glucose and lipid metabolic pathways, which are impaired in obesity and diabetes.Objectives: We evaluated the effects of calorie-restricted diet therapy on the circulating levels of miR-33b and miR-29a in relationship to ...
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Background: MicroRNAs have recently been introduced as epigenetic regulators of glucose and lipid metabolic pathways, which are impaired in obesity and diabetes.Objectives: We evaluated the effects of calorie-restricted diet therapy on the circulating levels of miR-33b and miR-29a in relationship to glucose and lipid metabolic parameters in obese patients with type 2 diabetes mellitus (T2DM).Methods: This randomized clinical controlled trial was performed on 30 eligible obese women with T2DM, randomly divided into two groups (control group, n = 15; diet therapy group, n = 15) for 10 weeks. Ten healthy women with normal weight were enrolled at the baseline of the study as controls. Demographic information, dietary intake, and anthropometric and biochemical indices were obtained before and after the study. Circulating miR-33b and miR-29a were assessed for all subjects using quantitative RT-PCR, and the fold change of each circulating miRNA was compared between groups.Results: The circulating levels of miR-29a and miR-33b in the diabetic women were higher (0.40-fold) and lower (1.43-fold), respectively, than normal levels. Diet therapy significantly increased the circulating level of miR-33b (P = 0.023, 0.97-fold upregulation) to normal levels. This increase was independently correlated with caloric restriction (95%CI: -0.004 to -0.0001, P = 0.022) and 2hPPBS (95%CI: -0.009 to -0.001, P = 0.035). No remarkable change was observed in circulating levels of miR-29a.Conclusions: Our findings introduced a novel therapeutic effect of diet therapy on circulating miRNAs in obese patients with T2DM. MiR-33b is an important therapeutic target in the treatment and prevention of T2DM and its complications.
